Sometimes certain pre-written macro's can conflict with mq2melee doing it's skill activation (wont list it here, I'm not 100% positive on Lillu's policy on naming macros in these forums), but if you're running a mac (especially one that manages skill fires) you may try /endmac and see if those skills will fire via mq2melee without the mac running. If so, you have your answer, and the sollution lay in either reconfiguring your mac or abandoning mqmelee. At least, I ran into a similar situation with mine

(although my mac is UF dependent, and you being on titanium kinda eliminates the idea you're using mine

)