I played a zerker, wiz box, cleric bot until TOV. When I started in TOV I realized I needed more healing power, started a cleric box. When I started trying named in TOV I realized I needed stonewall- Warrior box. When I found that my warrior out damages my zerker, I made my warrior my main focus.
Dammur
Edit: I do wish I had a shammy in the mix for panther. I am also slowly working on gearing a rogue bot. You may find that your rogue bot can out aggro your zerker too, just need to be careful about that.