Thanks for the response.
I will try the MQ2FPS program. And update you guys with how it goes.
I currently use titanium since UF crashes on start up with a memory reference error. I know this is due to the resolution conflict between my monitors and the eqclient.ini but it just does not seem to work no matter what I change. Titanium crashed the same way but I was able to solve the issue by only running in 1920x1080 window mode.
Because of this I run 6 bots and 1 main all in 1920x1080 since any resolution change crashes the game. Whether before I load the client or after its already running any resolution change crashes the client. I suspect running 7 clients in such a high resolution is my main issue.
As for the poster's original question, I spread out my clients over 4 hard drives. Main on SSD, 2 bots on each of the other 3 hard drives. This significantly improved my loading times between zones but had little effect on the overall performance when battles get hectic.
I am running core i7 / 16g ram / 670 gtx. It would be so nice to be able to get UF working and run 7 clients at full resolution with no frame rate problems.
-Meepins