This topic has cropped up a few times in ooc this week.
Issue: You create a hotkey / social and when you log in the next day the hotkey is not there. Either you created it in game or inside the ini file.
Assumed fact: You installed eq to the default location, C:\Program Files\Everquest - or whatever the default would look like.
Solution: Move the eq folder. Windows Vista / 7 by default have write protection to the Program Files folder and a few others not related to this discussion. C:\EqTHF would be a good place and name for your thf install of eq. Another drive would be good as well.
Another useful thing you might need/want can be found at the following link for windows 7 users.
http://www.sevenforums.com/tutorials/11 ... reate.html
If you have uac enabled and forget to run as admin you can run into the same issue where the .ini file is not saved upon edits being made.